137283-66-0Relevant academic research and scientific papers
An improved method for the synthesis of active esters of N-protected amino acids and subsequent synthesis of dipeptides
Takeda,Ayabe,Suzuki,Konda,Harigaya
, p. 689 - 691 (2007/10/02)
4-Dimethylaminopyridine-catalyzed reaction of mixed carbonates 3 with N-protected amino acids 4 gave the corresponding active esters 5-9, from which dipeptides 11-18 were synthesized by aminolysis with amino acids 10.
A Convenient Synthesis of Peptide Using Oxallates
Takeda, Kazuyoshi,Sawada, Izumi,Suzuki, Akira,Ogura, Haruo
, p. 4451 - 4454 (2007/10/02)
The equimolar reactions of N-protected amino acids , amino acids or amino acid esters with oxallates (1a-1e) having active ester groups in the presence of pyridine in acetonitrile afforded the corresponding dipeptides via active esters in good yields.
