137302-68-2

Upstream product

• 50-00-0 formaldehyd 
• 137302-82-0 N-(1-piperazinylsulfonyl)-L-phenylalanyl-N-<1(S)-(cyclohexylmethyl)-3,3-difluoro-2(R)-hydroxy-4-<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>-4,5-didehydro-L-norvalinamide 
• 2038-03-1 4-(2-AMINOETHYL)MORPHOLINE 
• 103322-58-3 ethyl 4(S)-<(tert-butyloxycarbonyl)amino>-5-(cyclohexylmethyl)-2,2-difluoro-3(R)-hydroxypentanoate 
• 137302-30-8 1,1-dimethylethyl <1-<<<1(S)-(cyclohexylmethyl)-3,3-difluoro-2(R)-hydroxy-4-<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>amino>carbonyl>-3(S)-butenyl>carbamate 
• 137429-58-4 1,1-dimethylethyl <1(S)-(cyclohexylmethyl)-3,3-difluoro-2(R)-hydroxy-4-<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>carbamate 
• 118233-28-6 (3R,4S)-4-tert-Butoxycarbonylamino-5-cyclohexyl-2,2-difluoro-3-hydroxy-pentanoic acid 
• 134334-91-1 (1S,2R)-<1-(cyclohexylmethyl)-3,3-difluoro-4-<<2-(4-morpholino)ethyl>amino>-2-hydroxy-4-oxobutyl>amine 
• 98105-42-1 (S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-1-propanal 

Downstream Products

• 137302-75-1 N-<(4-methyl-1-piperazinyl)sulfonyl>-L-phenylalanyl-N-<1-(cyclohexylmethyl)-3,3-difluoro-4-<<2-(4-morpholinyl)ethyl>amino>-2,4-dioxobutyl>-4,5-didehydro-L-norvalinamide 

Relevant academic research and scientific papers

Design and Synthesis of Potent, Selective, and Orally Active Fluorine-Containing Renin Inhibitors

A series of primate renin inhibitors containing difluorocarbinol and difluoroketone groups at the P1 - P1' position have been synthesized and studied both in vitro and in vivo.In vitro, the compounds were evaluated as inhibitors of m