1373037-97-8

Basic information

• Product Name: C₁₈H₂₂F₃NO₃
• Synonyms: C₁₈H₂₂F₃NO₃
• CAS NO: 1373037-97-8
• Molecular Weight: 357.373
• Mol File: 1373037-97-8.mol

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₂F₃NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₂F₃NO₃(1373037-97-8)
• EPA Substance Registry System: C₁₈H₂₂F₃NO₃(1373037-97-8)

Safety Data

• Hazardous Substances Data: 1373037-97-8(Hazardous Substances Data)

Upstream product

• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 108-12-3 isopentanoyl chloride 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 63-91-2 L-phenylalanine 
• 1373038-24-4 C₂₁H₂₄F₇NO₃ 
• 1373037-98-9 C₂₁H₂₆F₃NO₃ 
• 1373037-72-9 (S)-4-benzyl-3-(2-cyclohexylacetyl)-5,5-dimethyloxazolidin-2-one 
• 2314-97-8 iodotrifluoromethane 
• 1312341-52-8 (S)-4-benzyl-5,5-dimethyl-N-(3-methylbutanoyl)-1,3-oxazolidin-2-one 
• 503-74-2 3-methylbutyric acid 

Relevant articles and documents

A simple method for asymmetric trifluoromethylation of N-acyl oxazolidinones via Ru-catalyzed radical addition to zirconium enolates

A Ru-catalyzed direct thermal trifluoromethylation and perfluoroalkylation of N-acyloxazolidinones has been developed. The reaction is experimentally simple and requires inexpensive reagents while providing good yields of products with good levels of stereocontrol. Preliminary studies have shown notable compatibility with functional groups, aromatics, and certain heteroaromatic substituents. The described method provides a useful alternative for the synthesis of fluorinated materials in an experimentally convenient manner.