1373046-75-3 Usage
Uses
Used in Pharmaceutical Industry:
rac-4-(2-AMino-3,3-diMethyl-1-oxobutyl)benzonitrile Hydrochloride is used as a reagent for the synthesis of phenyloxobutanylpyridinylpiperazinecarboxamide derivatives. These derivatives possess TRPA1 receptor antagonistic properties, making them valuable in the development of medications targeting various conditions related to the TRPA1 receptor, such as pain, inflammation, and respiratory disorders.
The compound's role in the pharmaceutical industry is crucial, as it enables the creation of novel therapeutic agents with the potential to alleviate symptoms and improve the quality of life for patients suffering from a range of health issues. By facilitating the synthesis of TRPA1 receptor antagonists, rac-4-(2-AMino-3,3-diMethyl-1-oxobutyl)benzonitrile Hydrochloride contributes to the advancement of medical research and the development of innovative treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 1373046-75-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,0,4 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1373046-75:
(9*1)+(8*3)+(7*7)+(6*3)+(5*0)+(4*4)+(3*6)+(2*7)+(1*5)=153
153 % 10 = 3
So 1373046-75-3 is a valid CAS Registry Number.
1373046-75-3Relevant academic research and scientific papers
TRPA1 ANTAGONIST COMPOUNDS
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Page/Page column 52, (2014/12/12)
Compounds of Formula (I), pharmaceutically acceptable salts thereof, diastereomers, enantiomers, or mixtures thereof: wherein R1, R2, R3, X, Yn and A are as defined in the specification, as well as pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
TRPA1 RECEPTOR ANTAGONIST
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Page/Page column 18, (2012/05/04)
A compound of Formula (I), pharmaceutically acceptable salts thereof, enantiomers, or mixtures thereof: pharmaceutical compositions containing said compounds, enantiomers or mixtures, processes for making said compounds, enantiomers or mixtures, the use of said compounds, enantiomers or mixtures, and medicaments containing the same for treatment of pain and other conditions, and methods of treating pain and other conditions with the same.