137305-06-7

Upstream product

• 137272-89-0 methyl 3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)-1H-pyrazole-5-carboxylate 
• 52492-49-6 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-(N-nitrosoacetamido)-D-allitol 
• 137272-88-9 1-acetamido-2,5-anhydro-3,4,6-tri-O-benzoyl-1-deoxy-D-allitol 
• 137272-74-3 1-amino-2,5-anhydro-3,4,6-tri-O-benzoyl-1-deoxy-D-allitol 
• 68628-85-3 1-acetamido-2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-D-allitol 
• 73853-56-2 N-((2S,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-ylmethyl)-acetamide 
• 23316-67-8 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile 

Relevant academic research and scientific papers

A convenient synthesis of 4-deoxypyrazofurin

A preparation of 3-β-D-ribofuranosyl-1H-pyrazole-5-carboxamide (4-deoxypyrazofurin, 3) is reported in nine steps (in an overall yield of 21%) beginning with 2,5-anhydro-3,4,6-tri-O-benzoyl-D-allonitrile (6) and proceeding via a 1,3-dipolar cycloaddition reaction between methyl propiolate and 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-diazo-D-allitol (4).