1373162-40-3

Upstream product

• 886362-07-8 4-(methyloxy)-1H-indazol-3-amine 
• 1240518-05-1 1,1-dimethylethyl 3-amino-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-06-2 1,1-dimethylethyl 3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-09-5 1,1-dimethylethyl 3-{bis[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-10-8 5-chloro-N-[(5-chloro-2-thienyl)sulfonyl]-N-[4-(methyloxy)-1H-indazol-3-yl]-2-thiophenesulfonamide 
• 1373162-34-5 C₂₇H₂₄Cl₂N₄O₆S₄ 
• 1240518-07-3 1,1-dimethylethyl 3-[[(5-chloro-2-thienyl)sulfonyl]({[2-(trimethylsilyl)ethyl]oxy}methyl)amino]-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1373162-53-8 C₂₉H₃₇ClN₄O₅S₂Si 
• 94088-46-7 2-fluoro-6-methoxybenzonitrile 

Relevant academic research and scientific papers

Lead optimisation of the N1 substituent of a novel series of indazole arylsulfonamides as CCR4 antagonists and identification of a candidate for clinical investigation

Synthesis and preliminary SAR of the N1 substituent of a novel series of indazole sulfonamide chemokine receptor 4 (CCR4) antagonist is reported. Compound 7r was identified for further development.