94088-46-7

Basic information

• Product Name: 2-Fluoro-6-methoxybenzonitrile
• Synonyms: BUTTPARK 45\03-64;6-FLUORO-O-ANISONITRILE;2-FLUORO-6-METHOXYBENZONITRILE;2-CYANO-3-FLUOROANISOLE;2-Fluoro-6-Methoxycyanobenzene;2-Fluoro-6-methoxybenzonitrile 98%;2-Fluoro-6-methoxybenzonitrile98%;2-FLUORO-6-DIMETHOXYBENZONITRILE
• CAS NO: 94088-46-7
• Molecular Formula: C₈H₆FNO
• Molecular Weight: 151.14
• EINECS: 302-047-5
• Product Categories: Aromatic Nitriles;Phenyls & Phenyl-Het;C8 to C9;Cyanides/Nitriles;Nitrogen Compounds;Aryl Fluorinated Building Blocks;Building Blocks;C7-C8;C8 to C9;Chemical Synthesis;Fluorinated Building Blocks;Nitrogen Compounds;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks
• Mol File: 94088-46-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 103-105 °C(lit.)
• Boiling Point: 232.1 °C at 760 mmHg
• Flash Point: 94.1 °C
• Appearance: /
• Density: 1.18 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• BRN: 4179192
• CAS DataBase Reference: 2-Fluoro-6-methoxybenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-6-methoxybenzonitrile(94088-46-7)
• EPA Substance Registry System: 2-Fluoro-6-methoxybenzonitrile(94088-46-7)

Safety Data

• Hazard Codes: Xi,T,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36
• RIDADR: 3276
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 94088-46-7(Hazardous Substances Data)

Usage

Chemical Properties

White crystals

General Description

2-Fluoro-6-methoxybenzonitrile (FMBN) is a fluorinated organic building block used in organic synthesis. Molecular structure and vibrational spectra of FMBN have been investigated.

InChI:InChI=1/C8H6FNO/c1-11-8-4-2-3-7(9)6(8)5-10/h2-4H,1H3

Upstream product

• 1897-52-5 2,6 difluorobenzonitrile 
• 124-41-4 sodium methylate 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 67-56-1 methanol 
• 146137-74-8 2-fluoro-6-methoxybenzaldehyde 
• 171179-83-2 2-fluoro-6-methoxybenzaldoxime 

Downstream Products

• 177995-40-3 4-methoxy-3-amino-1,2-benzisoxazole 
• 231621-23-1 2,4-dihydroxy-6,6'-dimethoxy-2'-fluoro-3-(methoxycarbonyl)-benzophenone-N-(2-methylethyl)ketimine 
• 140675-43-0 2-Fluoro-6-hydroxybenzonitrile 
• 882695-42-3 4-(2-Cyano-3-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 120484-50-6 1-(2-Fluoro-6-methoxyphenyl)ethanone 
• 53005-47-3 2-Cyano-3-methoxyphenylacetonitril 
• 1214366-31-0 2-fluoro-6-methoxybenzylammonium chloride 
• 126940-15-6 3-amino-4-hydroxy-1,2-benzisoxazole 
• 688781-59-1 4-(2-fluoro-4-nitrophenoxy)-1,2-benzisoxazol-3-amine 
• 688781-61-5 4-(4-amino-2-fluorophenoxy)-1,2-benzisoxazol-3-amine 
• 1428478-66-3 3-bromo-2-fluoro-6-methoxybenzonitrile 

Relevant articles and documents

One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment

In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes.

IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R3, R4, R6, and R7 are as defined herein.

USE OF A QUINAZOLINE COMPOUND IN PREPARING A MEDICAMENT AGAINST FLAVIVIRIDAE VIRUS

Disclosed is a use of a quinazoline compound of Formula I having 2,4-diaminoquinazoline as a parent nucleus in preparation of a medicament for treating diseases caused by flaviviridae infection, especially a use in combating Hepatitis C virus infection and Dengue fever virus infection.