1373162-50-5

Basic information

• Product Name: C₂₆H₃₃ClN₄O₄S₂Si
• CAS NO: 1373162-50-5
• Molecular Weight: 593.243
• Mol File: 1373162-50-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₃ClN₄O₄S₂Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₃ClN₄O₄S₂Si(1373162-50-5)
• EPA Substance Registry System: C₂₆H₃₃ClN₄O₄S₂Si(1373162-50-5)

Safety Data

• Hazardous Substances Data: 1373162-50-5(Hazardous Substances Data)

Upstream product

• 94088-46-7 2-fluoro-6-methoxybenzonitrile 
• 1240518-07-3 1,1-dimethylethyl 3-[[(5-chloro-2-thienyl)sulfonyl]({[2-(trimethylsilyl)ethyl]oxy}methyl)amino]-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-06-2 1,1-dimethylethyl 3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-05-1 1,1-dimethylethyl 3-amino-4-(methyloxy)-1H-indazole-1-carboxylate 
• 1240518-08-4 5-chloro-N-[4-(methyloxy)-1H-indazol-3-yl]-N-({[2-(trimethylsilyl)ethyl]oxy}methyl)-2-thiophenesulfonamide 
• 771579-16-9 C₈H₁₀BrN 
• 886362-07-8 4-(methyloxy)-1H-indazol-3-amine 

Downstream Products

• 1240518-83-5 N-[1-{[3-(aminomethyl)phenyl]methyl}-4-(methyloxy)-1H-indazol-3-yl]-5-chloro-2-thiophenesulfonamide 

Relevant articles and documents

Lead optimisation of the N1 substituent of a novel series of indazole arylsulfonamides as CCR4 antagonists and identification of a candidate for clinical investigation

Synthesis and preliminary SAR of the N1 substituent of a novel series of indazole sulfonamide chemokine receptor 4 (CCR4) antagonist is reported. Compound 7r was identified for further development.