1373232-20-2 Usage
Uses
Used in Pharmaceutical Research and Development:
(S)-4,4-dimethylpyrrolidine-3-carboxylic acid is used as a building block in the synthesis of pharmaceutical drugs. Its application is due to its versatile chemical properties and structure, which allow for the creation of a variety of drug candidates.
Used in Agrochemical Production:
(S)-4,4-dimethylpyrrolidine-3-carboxylic acid is also utilized in the production of certain agrochemicals, where its unique chemical characteristics contribute to the development of effective products for the agricultural industry.
Used in Asymmetric Catalysis:
(S)-4,4-dimethylpyrrolidine-3-carboxylic acid has been investigated for its potential as an asymmetric catalyst in various chemical reactions. Its application in this field is due to the compound's unique stereochemistry, which can influence the selectivity of reactions and improve the synthesis of enantiomerically pure compounds.
Overall, (S)-4,4-dimethylpyrrolidine-3-carboxylic acid is a versatile compound with applications in multiple industries, including pharmaceuticals, agrochemicals, and as a catalyst in chemical reactions, thanks to its distinctive chemical properties and structure.
Check Digit Verification of cas no
The CAS Registry Mumber 1373232-20-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,2,3 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1373232-20:
(9*1)+(8*3)+(7*7)+(6*3)+(5*2)+(4*3)+(3*2)+(2*2)+(1*0)=132
132 % 10 = 2
So 1373232-20-2 is a valid CAS Registry Number.
1373232-20-2Relevant academic research and scientific papers
Enantioselective synthesis of gabapentin analogues via organocatalytic asymmetric Michael addition of α-branched aldehydes to β-nitroacrylates
Yoshida, Masanori,Masaki, Erika,Ikehara, Hiroto,Hara, Shoji
experimental part, p. 5289 - 5297 (2012/08/08)
Michael addition reaction of α-branched aldehydes to β-nitroacrylates was successfully carried out by using a mixed catalyst consisting of a primary amino acid, l-phenylalanine, and its lithium salt to give β-formyl-β′-nitroesters having a quaternary carbon centre in good yields (up to 85%) with high enantioselectivity (up to 98% ee). By using benzyl β-nitroacrylates as Michael acceptors, the obtained β-formyl-β′-nitroesters were converted into various 4,4-disubstituted pyrrolidine-3-carboxylic acids including analogues of gabapentin (Neurotin) in one step from the Michael adducts in high yields. The Royal Society of Chemistry 2012.
