137326-16-0

Upstream product

• 137360-93-1 Benzoic acid 1-((2R,3S,4S,5R,6R)-1-benzyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-yl)-4-hydroxy-butyl ester 
• 137326-14-8 Benzoic acid 1-((2R,3S,4S,5R,6R)-1-benzyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-yl)-but-3-enyl ester 
• 104343-31-9 2,6-dideoxy-2,6-<<(phenylmethoxy)carbonyl>imino>-1,3,4,5-tetrakis-O-(phenylmethyl)-D-glycero-L-gulo-heptitol 
• 137326-13-7 1-((2R,3S,4S,5R,6R)-1-Benzyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-yl)-but-3-en-1-ol 
• 137326-11-5 [2R-(2α,3α,4β,5α,6β)]-3,4,5-tris (phenylmethoxy)-6-[(phenylmethoxy)methyl]-1-(phenylmethyl)-2-piperidinemethanol 
• 137326-12-6 (2S,3S,4S,5R,6R)-1-Benzyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidine-2-carbaldehyde 
• 110205-71-5 2,6-dideoxy-2,6-imino-1,3,4,5-tetrakis-O-(phenylmethyl)-D-glycero-L-gulo-heptitol 
• 137326-15-9 Benzoic acid (1S,6R,7R,8S,9S,9aR)-7,8,9-tris-benzyloxy-6-benzyloxymethyl-octahydro-quinolizin-1-yl ester 

Relevant academic research and scientific papers

SYNTHESIS OF POLYHYDROXYLATED INDOLIZIDINE AND QUINOLIZIDINE COMPOUNDS -- POTENT INHIBITORS OF α-GLUCOSIDASE I

Polyhydroxylated indolizidine 6a and quinolizidine 6b were synthesized from a common precursor, iminoheptitol 8.The target compounds are potent inhibitors of the glycoprotein trimming enzyme -- α-glucosidase I.

HYDROXYMETHYL-INDOLIZIDINES AND QUINOLIZIDINES AND THEIR USE AS alpha-GLUCOSIDASE I INHIBITORS

The present invention describes a group of polyhydroxylated indolizidines and quinolizidines and their esters. These compounds are prepared starting from 2,6-dideoxy-2,6-dideoxy-2,6-imino-1,3,4,5-tetrakis-O- (phenylmethyl)-D-glycero-L-gulo-heptitol or a c