1373278-84-2

Upstream product

• 1373278-14-8 tert-butyl 5-(3-(4-fluorophenyl)-7-((hydroxyimino)methyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 
• 1373278-13-7 tert-butyl 5-(3-(4-fluorophenyl)-7-formyl-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 
• 1373278-12-6 tert-butyl 5-(3-(4-fluorophenyl)-7-(methoxy(methyl)carbamoyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 
• 1373278-11-5 2-(5-tert-butoxy-5-oxopentyl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid 
• 1373278-10-4 methyl 2-(5-tert-butoxy-5-oxopentyl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylate 
• 1373278-09-1 methyl 2-chloro-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylate. 
• 1373278-83-1 tert-butyl 5-(3-(4-fluorophenyl)-7-((S)-5-((S)-hydroxy(phenyl)methyl)-5-methyl-4,5-dihydroisoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 
• 4383-08-8 (S)-(+)-2-methyl-1-phenyl-2-propen-1-ol 
• 917889-25-9 3-(4-fluoro-phenyl)-2,4-dioxo-1,2,3,4-tetrahydro-quinazoline-7-carboxylic acid methyl ester 
• 103729-80-2 2-methyl-1-phenylprop-2-en-1-ol 
• 5372-81-6 dimethyl aminoterephthalate 
• 1195-45-5 para-fluorophenyl isocyanate 

Downstream Products

• 1373277-55-4 (R)-5-(7-(5-benzyl-5-methyl-4,5-dihydroisoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid 

Relevant academic research and scientific papers

QUINAZOLINONE-TYPE COMPOUNDS AS CRTH2 ANTAGONISTS

This application provides for compounds of the formula Formula I or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTH2 receptor.