103729-80-2Relevant academic research and scientific papers
Tellurium in the 'no-solvent' organic synthesis of allylic alcohols
Xu, Qinyu,Chao, Bin,Wang, Yongmei,Dittmer, Donald C.
, p. 12131 - 12146 (1997)
Elemental tellurium can be reduced by rongalite (HOCH2SO2Na·2H2O)-KOH in the solid phase by application of ultrasound or by microwave irradiation. Without solvent, the organic substrate leg sulfonate ester of an oxiranemethanol) is added with further sonication or irradiation to yield the desired organic product leg allylic alcohols) and elemental Te which may be recycled Phase-transfer conditions (water-toluene) also are satisfactory.
Lewis acid promoted highly stereoselective rearrangement of 2,3-aziridino alcohols: A new efficient approach to β-amino carbonyl compounds
Wang, Bao Min,Song, Zhen Lei,Fan, Chun An,Tu, Yong Qiang,Shi, Yian
, p. 363 - 366 (2002)
Equation Presented n=0,1 R1, R2 = H, alkyl, aryl A new Lewis acid promoted rearrangement reaction of 2,3-aziridino alcohols was discovered, which involved the highly stereoselective construction of a diastereogenic quaternary carbon
Proton-accelerated Lewis acid catalysis for stereo- And regioselective isomerization of epoxides to allylic alcohols
Baba, Misako,Hayashi, Satoshi,Hirabe, Rina,Noji, Masahiro,Takanami, Toshikatsu
supporting information, p. 7104 - 7107 (2021/07/28)
The isomerization of epoxides to allylic alcohols was developedviaproton-accelerated Lewis acid catalysis. The addition oftBuOH as a proton source is the key to the efficient catalytic cycle. Trisubstituted epoxides, including enantioenriched derivatives, were selectively converted to secondary-allylic alcohols without loss of enantiopurity.
Nazarov cyclization of divinyl and arylvinyl epoxides: Application in the synthesis of resveratrol-based natural products
Sudhakar, Gangarajula,Satish, Kovela
supporting information, p. 6475 - 6480 (2015/04/22)
New variation in the Nazarov cyclization has been developed by preparing divinyl and arylvinyl epoxides as pentadienyl cation precursors for the first time. Highly substituted cyclopentadienes, hydrindienes, and indenes were synthesized to demonstrate the compatibility of this reaction with substrates bearing a variety of substitutions and having different types of epoxides. Application of this method in the synthesis of resveratrol-based natural products was also demonstrated.
Palladium-catalyzed cross-coupling of unactivated alkenes with acrylates: Application to the synthesis of the C13-C21 fragment of palmerolide A
Wen, Zhen-Kang,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 13284 - 13287,4 (2012/12/12)
Diene to meet: A palladium-catalyzed cross-coupling reaction between alkyl-substituted olefins and acrylates gives the corresponding butadienes in moderate yield and stereoselectivity. This atom-economical reaction, which forms C sp 2-C sp 2 bonds, tolerates a wide range of allylic and homoallylic alcohols, and acrylates (see scheme; TIPS =triisopropylsilyl). The methodology was applied to the synthesis of the C13-C21 fragment of palmerolide A.
Palladium-catalyzed cross-coupling of unactivated alkenes with acrylates: Application to the synthesis of the C13-C21 fragment of palmerolide A
Wen, Zhen-Kang,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 13284 - 13287 (2013/01/15)
Diene to meet: A palladium-catalyzed cross-coupling reaction between alkyl-substituted olefins and acrylates gives the corresponding butadienes in moderate yield and stereoselectivity. This atom-economical reaction, which forms C sp 2-C sp 2 bonds, tolerates a wide range of allylic and homoallylic alcohols, and acrylates (see scheme; TIPS =triisopropylsilyl). The methodology was applied to the synthesis of the C13-C21 fragment of palmerolide A.
Kinetic resolution of aryl alkenylcarbinols catalyzed by Fc-PIP
Hu, Bin,Meng, Meng,Jiang, Shanshan,Deng, Weiping
, p. 1289 - 1294 (2012/08/28)
An effective kinetic resolution of a variety of aryl alkenylcarbinols catalyzed by nonenzymatic acyl transfer catalyst Fc-PIP was developed, affording corresponding unreacted alcohols in good to excellent ee value up to 99% and with selectivity factors up to 24.
QUINAZOLINONE-TYPE COMPOUNDS AS CRTH2 ANTAGONISTS
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Page/Page column 116, (2012/05/04)
This application provides for compounds of the formula Formula I or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTH2 receptor.
Manganese(III) acetate mediated oxidative radical cyclizations. Toward vicinal all-carbon quaternary stereocenters
Logan, Angus W.J.,Parker, Jeremy S.,Hallside, Michal S.,Burton, Jonathan W.
supporting information; experimental part, p. 2940 - 2943 (2012/08/28)
Manganese(III) acetate mediated oxidative radical cyclizations have been used to synthesize a range of densely functionalized and sterically congested cyclopentane-lactones. A number of the resulting lactones contain vicinal all-carbon quaternary stereocenters adjacent to a tertiary benzylic stereocenter and are formed with high levels of stereocontrol.
Synthesis of the c1-c14 fragment of sarcoglaucol-16-one via z -selective ando-type horner-wadsworth-emmons olefination
Gastl, Christoph,Laschat, Sabine
supporting information; experimental part, p. 2643 - 2651 (2010/10/01)
A synthetic strategy involving a Z-selective Horner-Wadsworth-Emmons olefination was developed for the preparation of the sarcoglaucolone precursor methyl (2Z,6E)-8-(methoxymethoxy)-6-methyl-2-[(3E)-4-methyl-5-oxopent-3-enyl]-9- [(trimethylsilyl)methyl]deca-2,6,9-trienoate. The target compound was isolated in a E/Z ratio of 17:83 Georg Thieme Verlag Stuttgart New York.
