137331-57-8

Basic information

• Product Name: Ethanone, 1-(8-methyl-8-azabicyclo[3.2.1]oct-2-en-2-yl)- (9CI)
• Synonyms: Ethanone, 1-(8-methyl-8-azabicyclo[3.2.1]oct-2-en-2-yl)- (9CI)
• CAS NO: 137331-57-8
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.2322
• Product Categories: ACETYLGROUP
• Mol File: 137331-57-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(8-methyl-8-azabicyclo[3.2.1]oct-2-en-2-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(8-methyl-8-azabicyclo[3.2.1]oct-2-en-2-yl)- (9CI)(137331-57-8)
• EPA Substance Registry System: Ethanone, 1-(8-methyl-8-azabicyclo[3.2.1]oct-2-en-2-yl)- (9CI)(137331-57-8)

Safety Data

• Hazardous Substances Data: 137331-57-8(Hazardous Substances Data)

Upstream product

• 135615-44-0 2-Acetyl-8-((2-(trimethylsilyl)ethoxy)carbonyl)-8-azabicyclo<3.2.1>octa-2,6-diene 
• 135615-45-1 2-Acetyl-8-((2-(trimethylsilyl)ethoxy)carbonyl)-8-azabicyclo<3.2.1>oct-2-ene 
• 132524-93-7 3-Diazo-4-penten-2-one 
• 13891-87-7 pent-4-en-2-one 
• 155930-75-9 2-Propionyl-8-aza-bicyclo[3.2.1]octa-2,6-diene-8-carboxylic acid tert-butyl ester 
• 155930-76-0 8-<(1,1-dimethylethoxy)carbonyl>-2-propionyl-8-azabicyclo<3.2.1>octa-2-ene 
• 5176-27-2 N-tert-butyloxycarbonyl-pyrrole 
• 177980-54-0 3-(phenylsulfonyl)-8-[(4-methylphenyl)sulfonyl]-8-azabicyclo[3.2.1]-2-octene 
• 316129-46-1 3-(phenylsulfonyl)-8-[(4-methylphenyl)sulfonyl]-2-(1-nitroethyl)-8-azabicyclo[3.2.1]octane 
• 316129-47-2 2-acetyl-8-[(4-methylphenyl)sulfonyl]-3-(phenylsulfonyl)-8-azabicyclo[3.2.1]octane 
• 316129-49-4 2-(2-methyl-1,3-dioxolan-2-yl)-8-[(4-methylphenyl)sulfonyl]-8-azabicyclo[3.2.1]oct-2-ene 
• 316129-48-3 1-acetyl-8-[(4-methylphenyl)sulfonyl]-8-azabicyclo[3.2.1]oct-2-ene 
• 50-00-0 formaldehyd 
• 316129-50-7 2-(2-methyl-1,3-dioxolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene 

Relevant articles and documents

BF3-induced rearrangement of aziridino cyclopropanes derived from 2-phenylsulfonyl 1,3-dienes. Application to the total synthesis of (±)-ferruginine

Total synthesis of the alkaloid (±)-ferruginine (1) has been developed via the 2-phenylsulfonyl 1,3-diene approach. BF3-induced rearrangement of the N-protected cyclohexane aziridino cyclopropane 8, derived from its corresponding epoxy cyclopropane, afforded the desired tropane alkaloid skeleton 9 in good yield. Michael addition of nitroethane (as an acyl anion equivalent) and transformation of the nitro group of the adduct 10 to a keto function gave 11. Elimination of benzenesulfinic acid and subsequent replacement of the tosyl group by a methyl group afforded the title compound 1.

Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment

Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds which are azabicyclo[2.2.1]oximes, azabicyclo[2.2.2]oximes, azabicyclo[2.2.1]amines, azabicyclo[2.2.2]amines, azabicyclo[3.2.1]oximes, and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 3 to 7 carbon atoms are disclosed.