137332-55-9 Usage
General Description
"(5S)-8-fluoro-5-methyl-6-(3-methylbut-2-en-1-yl)-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepine-2(1H)-thione" is a complex chemical compound with potential pharmaceutical applications. It belongs to the class of benzodiazepines, which are known for their sedative and anxiety-reducing effects. The presence of a fluoro group and a methyl substituent in the compound's structure indicates potential for modifying its pharmacological properties. The 6-(3-methylbut-2-en-1-yl) side chain adds to the complexity and potential diversity of its biological activities. Further research and studies are likely needed to fully understand the implications and potential uses of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 137332-55-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,3 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137332-55:
(8*1)+(7*3)+(6*7)+(5*3)+(4*3)+(3*2)+(2*5)+(1*5)=119
119 % 10 = 9
So 137332-55-9 is a valid CAS Registry Number.
137332-55-9Relevant articles and documents
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5- methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 4
Ho,Kukla,Breslin,Ludovici,Grous,Diamond,Miranda,Rodgers,Ho,De Clercq,Pauwels,Andries,Janssen,Janssen
, p. 794 - 802 (2007/10/02)
In previous papers, we have described the discovery of a new series of compounds, 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin- 2(1H)-ones, TIBO (1 and 1a), with potent anti-HIV-1 activity and the synthesis of analogues to better define
Regioselectivity in Intramolecular Nucleophilic Aromatic Substitution. Synthesis of the Potent Anti HIV-1 8-Halo TIBO Analogues
Parker, Kathlyn A.,Coburn, Craig A.
, p. 97 - 100 (2007/10/02)
Regioselective intramolecular nucleophilic substitution of 2,6-dihalo-3-nitrobenzyl diamines 2b and 2c gave benzodiazepines 3.These intermediates are useful in the preparation of the 8-halo TIBO derivatives 1, inhibitors of HIV-I replication in cell cultu
