1373349-01-9Relevant academic research and scientific papers
Nickel-catalyzed C-H direct amination of benzoxazoles with secondary amines
Li, Yaming,Liu, Jin,Xie, Yusheng,Zhang, Rong,Jin, Kun,Wang, Xiuna,Duan, Chunying
, p. 3715 - 3720 (2012)
In this article, a facile, efficient and practical method for Ni-catalyzed direct C-H amination of benzoxazole with secondary amines has been developed. This procedure requires Ni(OAc)2·4H2O as catalyst, TBHP as oxidant and acid as the additive. A variety of substituted benzoxazol-2-amines were synthesized in moderate to good yields.
