1373396-39-4Relevant articles and documents
Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
Prechter, Agnes,Groeger, Harald,Heinrich, Markus R.
supporting information; experimental part, p. 3384 - 3387 (2012/06/01)
The kinetic enzymatic resolution of azo acetates via aminolysis with Candida antarctica lipase B has been investigated using benzylamine as amine component. The products obtained from this biotransformation in high enantiomeric purity can serve as valuable precursors for various amino alcohols, as exemplified by the synthesis of the serotonin reuptake inhibitor (S)-(+)-cericlamine.