Cas 1373432-67-7,(S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid

1373432-67-7

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Basic information

Product Name: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid
Synonyms: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid
CAS NO:1373432-67-7
Molecular Formula:
Molecular Weight: 458.477
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid(CAS DataBase Reference)
NIST Chemistry Reference: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid(1373432-67-7)
EPA Substance Registry System: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(pyridin-2-ylmethyl)amino)butanoic acid(1373432-67-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1373432-67-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1373432-67-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,4,3 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1373432-67:
(9*1)+(8*3)+(7*7)+(6*3)+(5*4)+(4*3)+(3*2)+(2*6)+(1*7)=157
157 % 10 = 7
So 1373432-67-7 is a valid CAS Registry Number.

1373432-67-7Upstream product

21950-36-7 5'-amino-5'-deoxy-2',3'-O-isopropylideneadenosine

1373432-67-7Downstream Products

1373432-67-7Relevant academic research and scientific papers

Development of rationally designed DNA N6 adenine methyltransferase inhibitors

Hobley, Gerard,McKelvie, Jennifer C.,Harmer, Jenny E.,Howe, Jason,Oyston, Petra C.F.,Roach, Peter L.

, p. 3079 - 3082 (2012)

A series of bisubstrate inhibitors for DNA N6 adenine methyltransferase (Dam) have been synthesized by linking an amine analogue of S-adenosylmethionine to an aryl moiety designed to probe the binding pocket of the DNA adenine base. An initial structure-activity relationship study has identified substituents that increase inhibitor potency to the ～10 μM range and improve selectivity against the human cytosine methyltransferase Dnmt1.

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