137348-83-5

Upstream product

• 141-82-2 malonic acid 
• 14193-18-1 3,5-dinitrobenzaldehyde 

Downstream Products

• 146324-14-3 (E)-3-(3,5-Dinitro-phenyl)-acryloyl chloride 
• 42287-92-3 3-(3,5-dinitrophenyl)propanoic acid 
• 100098-75-7 (E)-2-(3,5-dinitrostyryl)-4,4-dimethyl-2-oxazoline hydrochloride 
• 100098-60-0 (E)-3,5-dinitro-N-(2-hydroxy-1,1-dimethylethyl) cinnamamide 

Relevant academic research and scientific papers

SUBSTITUTED 1,2,4-OXADIAZOLE, ITS APPLICATION AND A PHARMACEUTICAL PREPARATION COMPRISING IT

Substances effective against tuberculosis based on substituted 1,2,4-oxadiazoles of general formula I, where Y = S or CH2 and R = phenyl- or phenyl- substituted in positions 2, 3, 4, and 5 by one or several electron-acceptor groups or electron-donor groups. These compounds can be produced by easy syntheses and are characterized by low toxicity and high efficacy against mycobacteria, including multiresistant strains thereof. The invention also discloses a pharmaceutical preparation containing substituted 1,2,4-oxadiazole of formula I as active substance as well as the use of this substituted 1,2,4-oxadiazole as an antituberculosis drug.