1373494-46-2Relevant articles and documents
Cobalt-Catalyzed Direct Arylation of Imidazo[1,2-a]pyridine with Aryl Iodides
Babar, Dattatraya A.,Rode, Haridas B.
supporting information, p. 1823 - 1827 (2020/03/23)
The Co(II)Cl2·6H2O catalyzed C–H activation/direct arylation of imidazo[1,2-a]pyridine with aryl/heteroaryl iodide is reported. The cost effective, ligand and additive free protocol using KOAc successfully afforded 3-arylimidazo[1,2-
Regioselective direct c-3 arylation of imidazo[1,2- a ]pyridines with aryl tosylates and mesylates promoted by palladium-phosphine complexes
Choy, Pui Ying,Luk, Kwan Chak,Wu, Yinuo,So, Chau Ming,Wang, Lai-Lai,Kwong, Fuk Yee
, p. 1457 - 1463 (2015/02/19)
Direct C-3 arylation of imidazo[1,2-a]pyridines with aryl tosylates and mesylates has been accomplished by employing palladium(II) acetate associated with SPhos (2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) or L1 (2-(2-(diisopropylphosphino)phenyl)-1-methyl-1H-indole). This catalyst system can be applied to a wide range of aryl sulfonates and shows excellent C-3 regioselectivity of imidazo[1,2-a]pyridine. These results represent the first examples of using tosylate- and mesylate-functionalized arenes as the electrophile partners for this regioselective direct arylation.
Phosphine-free palladium-catalyzed direct arylation of imidazo[1,2-a] pyridines with aryl bromides at low catalyst loading
Fu, Hai Yan,Chen, Lu,Doucet, Henri
experimental part, p. 4473 - 4478 (2012/06/30)
Ligand-free Pd(OAc)2 was found to catalyze very efficiently the direct arylation of imidazo[1,2-a]pyridines at C3 under very low catalyst concentration. The reaction can be performed employing as little as 0.1-0.01 mol % catalyst with electron-
