49584-07-8

Basic information

• Product Name: 3-cyanophenyl-4-methylbenzene-1-sulfonate
• Synonyms: 3-cyanophenyl-4-methylbenzene-1-sulfonate
• CAS NO: 49584-07-8
• Molecular Weight: 273.312
• Mol File: 49584-07-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-cyanophenyl-4-methylbenzene-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyanophenyl-4-methylbenzene-1-sulfonate(49584-07-8)
• EPA Substance Registry System: 3-cyanophenyl-4-methylbenzene-1-sulfonate(49584-07-8)

Safety Data

• Hazardous Substances Data: 49584-07-8(Hazardous Substances Data)

Upstream product

• 873-62-1 m-cyanophenol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1011481-68-7 neopentyl 3-cyanobenzoate 
• 168619-12-3 methyl 1-(3'-cyano-biphenyl-3-yl)carboxylate 
• 154197-00-9 3-cyano-4'-methoxybiphenyl 
• 214360-46-0 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 
• 1877-72-1 3-Cyanobenzoic acid 
• 1373494-46-2 3-(imidazo[1,2-a]pyridin-3-yl)benzonitrile 
• 10406-24-3 3-(aminomethyl)benzonitrile 
• 1156122-53-0 2-{[(3-cyanophenyl)methyl]carbamoyl}benzoic acid 
• 85915-09-9 3-Cyanphenylphosphonsaeurediethylester 

Relevant articles and documents

Direct Carboxylation of Aryl Tosylates by CO2 Catalyzed by in situ-Generated Ni0

A novel Ni0-catalyzed carboxylation of aryl tosylates with carbon dioxide has been achieved under moderate temperatures and atmospheric pressure. In this procedure, the active Ni0 species is generated in situ by simply mixing the Ni0 precatalyst [NiBr2(bipy)] with an excess of manganese metal. This approach requires neither a glove-box nor the tedious preparation of sophisticated intermediate organometallic derivatives. This mild, convenient, and user-friendly process is successfully applied to the valorization of carbon dioxide and the synthesis of versatile reactants with broad tolerance of substituents.

Aminocarbonylation of Aryl Tosylates to Carboxamides

The palladium - catalyzed aminocarbonylation of aryl tosylates with amines is reported. Suitable conditions were identified by high throughput reaction screening and then further optimized. The substrate scope of the reaction with respect to the aryl tosylate component and the amine component are reported. Competitive aminolysis of the aryl tosylates to afford the amine toluenesulfonamides and the phenol was not observed.

Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls. Copyright