1373496-66-2

Upstream product

• 533-58-4 2-Iodophenol 
• 90794-32-4 2-([(ethoxycarbonyl)methylene]oxy)-1-iodobenzene 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1373496-79-7 C₂₂H₂₃N₃O₆ 
• 1373496-69-5 C₁₀H₈O₃ 
• 1373496-70-8 C₁₄H₁₇NO₂ 
• 1373496-80-0 C₂₅H₃₁N₅O₄ 
• 1373496-81-1 C₂₃H₂₇N₅O₄ 
• 1373496-77-5 C₁₆H₂₀N₂O₃ 
• 1373496-83-3 C₃₃H₄₅N₇O₆ 
• 108807-15-4 2-O-(ethoxycarbonylmethyl)benzoic acid 

Relevant academic research and scientific papers

DBU-mediated regioselective intramolecular cyclization/dehydration of ortho diketo phenoxyethers: A synthesis of 2,3-substituted γ-benzopyranones

The regioselective cyclization/dehydration sequence of ortho diketo phenoxyethers induced by DBU has been explored. The results demonstrated a high degree of selectivity with preference for 6-exo-trig cyclization leading to the formation of γ-benzopyranone derivatives in good yield.

A 1,4-diphenyl-1,2,3-triazole-based β-turn mimic constructed by click chemistry

A series of 1,4-diphenyl-1,2,3-triazole-incorporated amide derivatives have been designed and prepared. X-ray crystallographic and (1D and 2D) 1H NMR studies reveal that these compounds fold into stable U-shaped conformations driven by three-center intramolecular C-H???O hydrogen-bonding formed between the triazole C-5 H atom and the two ether O atoms. Such folded structures make this 1,4-diphenyl-1,2,3-triazole skeleton a good candidate to be used as β-turn mimic. To prove this, the formation of a β-hairpin structure induced by this β-turn motif has been further demonstrated.