1373497-77-8Relevant academic research and scientific papers
Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores
Sashidhara, Koneni V.,Kumar, Manoj,Modukuri, Ram K.,Srivastava, Rajeev Kumar,Soni, Awakash,Srivastava, Kumkum,Singh, Shiv Vardan,Saxena,Gauniyal, Harsh M.,Puri, Sunil K.
, p. 2971 - 2981 (2012/07/02)
A series of novel keto-enamine chalcone-chloroquine based hybrids were synthesized following new methodology developed in our laboratory. The synthesized compounds were screened against chloroquine sensitive strain (3D7) of Plasmodium falciparum in an in
Efficient and general synthesis of 3-aryl coumarins using cyanuric chloride 1
Sashidhara, Koneni V.,Palnati, Gopala Reddy,Avula, Srinivasa Rao,Kumar, Abdhesh
scheme or table, p. 611 - 621 (2012/03/27)
An efficient and general protocol for a rapid synthesis of different substituted 3-aryl coumarins is reported. A series of different substituted phenyl acetic acids have been successfully reacted with different substituted 2-hydroxy benzaldehydes in the presence of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and N-methyl morpholine to afford 3-aryl coumarins in good to excellent yields. Georg Thieme Verlag Stuttgart · New York.
