1373497-82-5Relevant academic research and scientific papers
Metal-free radical trifluoromethylation of β-nitroalkenes through visible-light photoredox catalysis
Midya, Siba P.,Rana, Jagannath,Abraham, Thomas,Aswin, Bhaskaran,Balaraman, Ekambaram
, p. 6760 - 6763 (2017/07/10)
A catalytic method for functional group interconversion is immensely important in modern sciences. Here, we report an efficient catalytic conversion of nitroalkenes to highly stereoselective 1-trifluoromethylalkenes at room temperature. This unprecedented metal-free photocatalytic strategy is simple and operates under visible-light irradiation using the commercially available CF3 source.
Simple synthesis of β-trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane
Omote, Masaaki,Tanaka, Miyuu,Ikeda, Akari,Nomura, Shiho,Tarui, Atsushi,Sato, Kazuyuki,Ando, Akira
supporting information; experimental part, p. 2286 - 2289 (2012/06/04)
(E)-Trimethyl-(3,3,3-trifluoroprop-1-enyl)silane (1) was synthesized as a reagent for use in Hiyama cross-coupling reactions for the production of β-trifluoromethylstyrene derivatives. Cross-coupling of 1 with electronically diverse aryl iodides was achieved by treatment with CsF in the presence of catalytic amounts of palladium to afford the desired products in moderate to good yields.
