692-51-3Relevant academic research and scientific papers
Selective nickel-catalyzed fluoroalkylations of olefins
Zhang, Shaoke,Weniger, Florian,Ye, Fei,Rabeah, Jabor,Ellinger, Stefan,Zaragoza, Florencio,Taeschler, Christoph,Neumann, Helfried,Brückner, Angelika,Beller, Matthias
supporting information, p. 15157 - 15160 (2020/12/21)
Mild and selective nickel-catalyzed trifluoromethylation and perfluoroalkylation reactions of alkenes were developed to provide fluorinated olefins, including natural products, pharmaceuticals, and variety of synthetic building blocks in good to excellent
Simple synthesis of β-trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane
Omote, Masaaki,Tanaka, Miyuu,Ikeda, Akari,Nomura, Shiho,Tarui, Atsushi,Sato, Kazuyuki,Ando, Akira
supporting information; experimental part, p. 2286 - 2289 (2012/06/04)
(E)-Trimethyl-(3,3,3-trifluoroprop-1-enyl)silane (1) was synthesized as a reagent for use in Hiyama cross-coupling reactions for the production of β-trifluoromethylstyrene derivatives. Cross-coupling of 1 with electronically diverse aryl iodides was achieved by treatment with CsF in the presence of catalytic amounts of palladium to afford the desired products in moderate to good yields.
