13735-11-0

Basic information

• Product Name: 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one
• Synonyms: 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one;6-Methoxy-2,3-dihydrothiochroMen-4-one;2,3-DIHYDRO-6-METHOXY-4H-1-BENZOTHIOPYRAN-4-ONE;6-methoxythiochroman-4-one
• CAS NO: 13735-11-0
• Molecular Formula: C₁₀H₁₀O₂S
• Molecular Weight: 194.2502
• Mol File: 13735-11-0.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one(13735-11-0)
• EPA Substance Registry System: 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one(13735-11-0)

Safety Data

• Hazardous Substances Data: 13735-11-0(Hazardous Substances Data)

Usage

General Description

6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one is a chemical compound that belongs to the class of benzothiinones. It is also known by the chemical name 3,4-Dihydro-6-methoxy-2H-1-benzothiin-4-one. 6-Methoxy-3,4-dihydro-2H-1-benzothiin-4-one is a derivative of benzothiinone and is characterized by a methoxy group at the 6th position of the benzene ring. It has potential applications in the field of organic synthesis and medicinal chemistry due to its structural features. Additionally, it may have biological activities, making it a compound of interest for further research and development in pharmaceutical and other chemical industries.

Upstream product

• 107-94-8 chloropropionic acid 
• 696-63-9 4-Methoxybenzenethiol 
• 13739-36-1 β-(4-methoxyphenylmercapto)propionic acid 
• 19488-09-6 sodium 4-methoxyphenylthiolate 

Downstream Products

• 145903-32-8 7-methoxy-3,4-dihydrobenzo[f][1,4]thiazepin-5(2H)-one 
• 110766-87-5 7-methoxy-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 927871-76-9 S107 
• 145903-31-7 7-methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine 
• 1315306-66-1 3-(4-chlorophenyl)-6'-methoxy-spiro[oxirane-2,3'-thiochroman]-4'-one 
• 115091-90-2 1-Benzo[1,3]dioxol-5-yl-3,6-dimethoxy-10H-9-thia-4-aza-phenanthrene-2-carbonitrile 
• 115091-89-9 3,6-Dimethoxy-1-(4-methoxy-phenyl)-10H-9-thia-4-aza-phenanthrene-2-carbonitrile 
• 130689-04-2 6-Methoxy-3-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-thiochroman-4-one 
• 130689-05-3 3-[1-Benzo[1,3]dioxol-5-yl-meth-(Z)-ylidene]-6-methoxy-thiochroman-4-one 

Relevant articles and documents

Synthesis of benzothiazonine by rhodium-catalyzed denitrogenative transannulation of 1-sulfonyl-1,2,3-triazole and thiochromone

A facile synthesis of multi-functionalized benzothiazonine was achieved by the rhodium-catalyzed denitrogenative annulation of 1-sulfonyl-1,2,3-triazole and thiochromone. In view of the excellent atom economy, broad substrate scope and easy availability of starting materials, the protocol provided an efficient strategy for the construction of mediumN,S-heterocycles.

Synthesis of Novel Pterocarpen Analogues via [3?+?2] Coupling-Elimination Cascade of α,α-Dicyanoolefins with Quinone Monoimines

By employing triethylamine as a catalyst, [3?+?2] coupling-elimination cascade of α,α-dicyanoolefins with quinone monoimines was realized. The reactions afforded various novel pterocarpen analogues with generally moderate yields (up to 75%). In addition, a plausible reaction mechanism was proposed.

Cu-Catalyzed Conjugate Addition of Grignard Reagents to Thiochromones: An Enantioselective Pathway for Accessing 2-Alkylthiochromanones

The enantioselective incorporation of alkyl groups in thiochromones was realized for the first time by a Cu/(R, S)-PPF-P t Bu 2 -catalyzed conjugate addition of Grignard reagents to thiochromones. With this method, a series of 2-methylthiochromanones were obtained in good yields (up to 96% yield) with moderate-to-good ee values (up to 87% ee). The established method expedites the synthesis of a large library of chiral thiochromanones for further synthetic applications and biological studies.