137368-84-4 Usage
Molecular weight
286.3
Chemical structure
A pyrazolo[4,3-c]pyridine ring with a carboxylic acid group at position 6, and an ethyl ester and two phenyl groups at position 1 and 4, respectively.
Appearance
Yellowish solid
Solubility
Poorly soluble in water, soluble in organic solvents like ethanol, methanol, and acetonitrile.
Biological activity
Modulates the activity of the GABAA receptor, potential therapeutic effects in the treatment of anxiety, depression, and other psychiatric disorders.
Neuroprotective and anti-inflammatory properties
Being studied for its potential neuroprotective and anti-inflammatory properties.
Limitations
More research is needed to fully understand the effects and potential applications of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 137368-84-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,6 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 137368-84:
(8*1)+(7*3)+(6*7)+(5*3)+(4*6)+(3*8)+(2*8)+(1*4)=154
154 % 10 = 4
So 137368-84-4 is a valid CAS Registry Number.
137368-84-4Relevant articles and documents
Pyrido annelation reaction by a tandem aza Wittig/electrocyclic ring-closure strategy: Preparation of pyrazolo[4,3-c]- and pyrazolo[3,4-c]pyridine derivatives
Molina,Aller,Lorenzo
, p. 6737 - 6746 (2007/10/02)
The aza Wittig-type reaction of iminophosphorane 3, prepared from 5-formyl-1-phenylpyrazole by sequential treatment with ethyl azidoacetate and triphenylphosphine, with isocyanates, ketenes, aldehydes and carbon disulfide leads to the functionalized pyrazolo[4,3-c]pyridines 5, 7, 9 and 11 respectively. Iminophosphorane 15, prepared from 4-formyl-1-phenylpyrazole, undergoes pyrido annelation by reaction with ketenes to give the isomeric pyrazolo[3,4-c]pyridines 22 in modest yields.
