1373693-91-4Relevant academic research and scientific papers
First syntheses of lorneic acids A and B with potential PDE5 inhibition activity
Ma, Xiang,Song, Yuting,Liu, Hao,Chen, Ruijiao,Chen, Xiaochuan
, p. 607 - 610 (2012/03/27)
Two natural products with potential PDE5 inhibition activity, lorneic acids A and B, have been synthesized for the first time in high yield using a chiral amide stereocontrolled addition of aryl lithium to aldehyde as the key step, and the configuration of the chiral benzylic alcohol in lorneic acid B was determined to be S. Georg Thieme Verlag Stuttgart · New York.
