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1373766-98-3

ethyl 7-methoxy-2-(3-(methylsulfonyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1373766-98-3 Structure

  • Basic information

    1. Product Name: ethyl 7-methoxy-2-(3-(methylsulfonyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
    2. Synonyms:
    3. CAS NO:1373766-98-3
    4. Molecular Formula:
    5. Molecular Weight: 401.44
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1373766-98-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl 7-methoxy-2-(3-(methylsulfonyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl 7-methoxy-2-(3-(methylsulfonyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate(1373766-98-3)
    11. EPA Substance Registry System: ethyl 7-methoxy-2-(3-(methylsulfonyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate(1373766-98-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1373766-98-3(Hazardous Substances Data)

1373766-98-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1373766-98-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,7,6 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1373766-98:
(9*1)+(8*3)+(7*7)+(6*3)+(5*7)+(4*6)+(3*6)+(2*9)+(1*8)=203
203 % 10 = 3
So 1373766-98-3 is a valid CAS Registry Number.

1373766-98-3Downstream Products

1373766-98-3Relevant articles and documents

Lead optimization of 3-carboxyl-4(1 H)-quinolones to deliver orally bioavailable antimalarials

Zhang, Yiqun,Clark, Julie A.,Connelly, Michele C.,Zhu, Fangyi,Min, Jaeki,Guiguemde, W. Armand,Pradhan, Anupam,Iyer, Lalitha,Furimsky, Anna,Gow, Jason,Parman, Toufan,El Mazouni, Farah,Phillips, Margaret A.,Kyle, Dennis E.,Mirsalis, Jon,Guy, R. Kiplin

, p. 4205 - 4219 (2012/07/02)

Malaria is a protozoal parasitic disease that is widespread in tropical and subtropical regions of Africa, Asia, and the Americas and causes more than 800,000 deaths per year. The continuing emergence of multidrug-resistant Plasmodium falciparum drives the ongoing need for the development of new and effective antimalarial drugs. Our previous work has explored the preliminary structural optimization of 4(1H)-quinolone ester derivatives, a new series of antimalarials related to the endochins. Herein, we report the lead optimization of 4(1H)-quinolones with a focus on improving both antimalarial potency and bioavailability. These studies led to the development of orally efficacious antimalarials including quinolone analogue 20g, a promising candidate for further optimization.

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