1373870-75-7

Upstream product

• 1207201-35-1 3-fluoro-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid 
• 903522-29-2 3,5-difluoro-4-pyridinecarboxylic acid 
• 1373870-91-7 3-fluoro-5-[(2-fluoro-4-iodophenyl)amino]isonicotinamide 
• 19962-06-2 tert-butyl 3-hydroxyphenylcarbamate 
• 29632-74-4 2-fluro-4-iodoaniline 

Downstream Products

• 1373870-77-9 3-[(2-fluoro-4-iodophenyl)amino]-5-{3-[(isopropylsulfonyl)amino]phenoxy}isonicotinamide 
• 1373870-83-7 3-[(2-fluoro-4-iodophenyl)amino]-5-[3-(isobutyrylamino)phenoxy]isonicotinamide 
• 1373870-81-5 3-(3-acetamidophenoxy)-5-[(2-fluoro-4-iodophenyl)amino]isonicotinamide 
• 1373870-80-4 3-{3-[(cyclopropylsulfonyl)amino]phenoxy}-5-[(2-fluoro-4-iodophenyl)amino]isonicotinamide 
• 1373870-78-0 3-[(2-fluoro-4-iodophenyl)amino]-5-{3-[(methylsulfonyl)amino]-phenoxy}isonicotinamide 
• 1373870-79-1 3-{3-[(ethylsulfonyl)amino]phenoxy}-5-[(2-fluoro-4-iodophenyl)-amino]isonicotinamide 

Relevant academic research and scientific papers

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

Having recently identified a so-far unexplored area adjacent to the known binding site of allosteric mitogen-activated protein kinase kinase (MEK) inhibitors, we now report an extension of these studies by combining our new side chains with different MEK

SUBSTITUTED PHENOXYPYRIDINES

The present invention relates to substituted phenoxypyridine compounds of general formula (I) in which R1, R2 and R3 are as defined in the claims, to methods of preparing said compounds, to intermediates for the preparation of said compounds, to pharmaceu