1373935-52-4

Basic information

• Product Name: tert-butyl N-[phenyl(2,4,6-trimethoxyphenyl)methyl]carbamate
• Synonyms: tert-butyl N-[phenyl(2,4,6-trimethoxyphenyl)methyl]carbamate
• CAS NO: 1373935-52-4
• Molecular Weight: 373.449
• Mol File: 1373935-52-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: tert-butyl N-[phenyl(2,4,6-trimethoxyphenyl)methyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl N-[phenyl(2,4,6-trimethoxyphenyl)methyl]carbamate(1373935-52-4)
• EPA Substance Registry System: tert-butyl N-[phenyl(2,4,6-trimethoxyphenyl)methyl]carbamate(1373935-52-4)

Safety Data

• Hazardous Substances Data: 1373935-52-4(Hazardous Substances Data)

Upstream product

• 621-23-8 1,2,3-trimethoxybenzene 
• 4248-19-5 tert-butyl carbazate 
• 100-52-7 benzaldehyde 
• 1612780-88-7 tert-butyl (phenyl(phenylthio)methyl)carbamate 
• 1323902-49-3 tert-butyl ((ethylthio)(phenyl)methyl)carbamate 
• 150884-50-7 benzaldehyde N-boc imine 

Downstream Products

• 1224969-79-2 3-(phenyl(2,4,5-trimethoxyphenyl)methyl)-1H-indole 
• 86694-47-5 2-methyl-5-[(5-methylfuran-2-yl)(phenyl)methyl]furan 

Relevant articles and documents

Facile synthesis of nonsymmetrical heteroaryl-substituted triarylmethanes: Via the FeCl3·6H2O-catalyzed two-step Friedel-Crafts-type reaction

The FeCl3·6H2O-catalyzed three-component aza-Friedel-Crafts reaction of aromatic/heteroaromatic compounds, aromatic aldehydes and tert-butyl carbamate was reported. The subsequent Friedel-Crafts-type alkylation of the resulting tert-

NIS-assisted aza-Friedel-Crafts reaction with α-carbamoysulfides as precursors of N-carbamoylimines

A general and practical N-iodosuccinimide (NIS)-promoted aza-Friedel-Crafts reaction of various aromatic nucleophiles with N-acylimines generated in situ from α-amidosulfides to give a rapid access to highly functionalized amines is described. The newly developed methodology is very mild, fast, efficient, and complementary.

Iodine-catalyzed, one-pot, three-component aza-Friedel-Crafts reaction of electron-rich arenes with aldehyde/carbamate combinations

Iodine is shown to be an efficient catalyst for a one-step, three-component aza-Friedel-Crafts reaction of activated arenes or heteroarenes with benzyl or tert-butyl carbamates in combination with a wide variety of aldehydes in toluene under 'open-flask'