1374229-48-7Relevant academic research and scientific papers
Synthesis of tetrasubstituted NH pyrroles and polysubstituted furans via an addition and cyclization strategy
Li, Liang,Zhao, Mi-Na,Ren, Zhi-Hui,Li, Jianli,Guan, Zheng-Hui
experimental part, p. 532 - 540 (2012/04/04)
The FeCl3-catalyzed addition and cyclization of enamino esters with nitroolefins provides a straightforward and general method for the synthesis of tetrasubstituted NH pyrroles. This novel method tolerates a wide range of functionality, and allows for rapid elaboration of the nitroolefins into a variety of substituted pyrroles in good yields. Further, an efficient KOAc-promoted addition and cyclization protocol toward substituted furans has been described as well. Georg Thieme Verlag Stuttgart · New York.
