1374309-31-5Relevant articles and documents
Visible-Light Induced and Oxygen-Promoted Oxidative Cyclization of Aromatic Enamines for the Synthesis of Quinolines Derivatives
Xia, Xiao-Feng,Zhang, Guo-Wei,Wang, Dawei,Zhu, Su-Li
, p. 8455 - 8463 (2017/08/23)
The dual transition metal-visible light photoredox catalysis for the synthesis of quinoline derivatives by using dioxygen as an oxygen source is developed. By using visible light, the direct oxidative cyclization of aromatic enamines with alkynes or alkenes can be achieved at mild conditions with an aid of copper or palladium catalysts, and a variety of multisubstituted quinoline derivatives could be obtained in good to moderate yields under mild reaction conditions.
Copper-Catalyzed Aerobic Oxidative Carbocyclization Reactions of N -[(E)-Stilben-2-yl]amine Derivatives
Lu, Cheng-Yen,Chuang, Che-Ping
, p. 3687 - 3700 (2015/11/28)
A synthetic method for highly functionalized 2-quinolinones and quinolines has been developed. The copper(II)-catalyzed aerobic oxidative carbocyclization reactions of α-substituted N-[(E)-stilben-2-yl]acetamides, via the intramolecular carbocupration onto the alkenyl moiety, produced 3-substituted 2-quinolinones. Several useful functional groups including benzoyl, acetyl, cyano, and ethoxycarbonyl groups are compatible with the reaction conditions. This strategy was further applied to N-[(E)-stilben-2-yl]enamines to prepare 2,3-disubstituted quinolines in good yields.
Copper-catalyzed oxidative cyclization of enynes for the synthesis of 4-carbonyl-quinolines with O2
Xia, Xiao-Feng,Zhang, Lu-Lu,Song, Xian-Rong,Liu, Xue-Yuan,Liang, Yong-Min
supporting information; experimental part, p. 2480 - 2483 (2012/07/13)
A novel copper-catalyzed oxidative cyclization of enynes and in situ formed enynes leading to 4-carbonyl-quinolines by using dioxygen as an oxygen source has been developed.
