1374328-49-0

Basic information

• Product Name: N,N-dimethyl-5-phenylpyridin-2-amine
• Synonyms: N,N-dimethyl-5-phenylpyridin-2-amine
• CAS NO: 1374328-49-0
• Molecular Weight: 198.268
• Mol File: 1374328-49-0.mol

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-5-phenylpyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-5-phenylpyridin-2-amine(1374328-49-0)
• EPA Substance Registry System: N,N-dimethyl-5-phenylpyridin-2-amine(1374328-49-0)

Safety Data

• Hazardous Substances Data: 1374328-49-0(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 1036991-24-8 N,N-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine 
• 26163-07-5 5-bromo-2-dimethylaminopyridine 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 

Relevant articles and documents

Synthesis of biaryls through a one-pot tandem borylation/Suzuki-Miyaura cross-coupling reaction catalyzed by a palladacycle

The tricyclohexylphosphane adduct of cyclopalladated ferrocenylimine I exhibited high catalytic activity in the one-pot borylation/Suzuki-Miyaura coupling (BSC) reaction with low catalyst loading (2 mol-%). Various biaryls were obtained in good to excellent yields for 37 examples. This process was applied to aryl and heteroaryl halides (Br and Cl) containing a variety of functional groups and did not require an excess amount of phosphane ligand and the addition of the palladium catalyst in the second step. Cyclopalladated ferrocenylimine I exhibited high catalytic activity in the borylation/Suzuki- Miyaura coupling (BSC) reaction with low catalyst loading. Various unsymmetrical biaryls were obtained ingood to excellent yields in one pot. This protocol was applied to aryl and heteroaryl halides (Br and Cl) containing a variety of functional groups without adding catalyst in the second step. Copyright