1374337-13-9

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 17903-36-5 1-bromo-4-methoxylphenyltrimethylsilane 
• 501-65-5 diphenyl acetylene 
• 17876-90-3 3-trimethylsilylanisol 
• 556812-41-0 4-methoxy-2-(trimethylsilyl)phenyl triflate 

Relevant academic research and scientific papers

Palladium-catalyzed cleavage of the Me-Si bond in ortho-trimethylsilyl aryltriflates: Synthesis of benzosilole derivatives from ortho-trimethylsilyl aryltriflates and alkynes

An efficient Pd-catalyzed cleavage of the Me-Si bond in ortho-trimethylsilyl aryltriflates was realized and synthetically applied. Most of the commercially available ortho-trimethylsilyl aryltriflates could undergo the Pd-catalyzed intermolecular coupling with alkynes via cleavage of the Me-Si bond, which represents a new reaction pattern of ortho-trimethylsilyl aryltriflates. Potassium bromide (KBr) was found effective for this process. A variety of benzosilole derivatives were thus generated in high yields. The Royal Society of Chemistry 2013.

Palladium-catalyzed intermolecular coupling of 2-silylaryl bromides with alkynes: Synthesis of benzosiloles and heteroarene-fused siloles by catalytic cleavage of the C(sp3)-Si bond

Unusual split: A wide variety of benzosiloles and derivatives are obtained by the Pd-catalyzed intermolecular coupling of 2-silylaryl bromides and alkynes and the accompanying selective cleavage of the C(sp3)-Si bonds as a key step (see scheme). The product spectrum includes benzosiloles, benzothiophene-fused siloles, ladder-type π-conjugated benzosiloles, and thiophene-bridged 2,5-bisbenzosiloles.