1374348-10-3Relevant articles and documents
Palladium-Catalyzed Decarboxylative Cross-Coupling of 1,3,4-Oxa-diazoles with Alkynoic Acids: A Simple Route for the Preparation of 2-Alkynylated 1,3,4-Oxadiazoles
Reddy, L. Madhava,Reddy, P. Raghavendar,Reddy, Ch. Krishna
, p. 1675 - 1679 (2017/03/21)
For the first time 2-alk-1-ynyl-5-(het)aryl-1,3,4-oxadiazole derivatives have been synthesized by the decarboxylative cross-coupling of alk-2-ynoic acids with 2-(het)aryl-1,3,4-oxadiazoles, employing palladium(II) chloride as the catalyst and silver(I) oxide as an oxidant with 1,3-bis(diphenylphosphanyl)propane as a ligand. Products were formed in high yields with no byproduct.
Copper-mediated C-H activation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes using PEG-400 as a solvent medium: Distinct approach for the alkynylation of 1,3,4-oxadiazoles
Reddy, Gandolla Chinna,Balasubramanyam, Penagaluri,Salvanna,Das, Biswanath
, p. 471 - 474 (2012/03/08)
The direct C-H alkynylation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes has been accomplished by using a combination of CuBr/LiOtBu in PEG-400 (a green solvent) at 80 °C. The products were formed in high yields (73-86%) in 2 h. No additional ligand or volatile solvent was required and the conversion was ecofriendly. The direct C-H alkynylation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes has been accomplished by using a combination of CuBr/LiOtBu in PEG-400 (a green solvent) at 80 °C. The products were formed in high yields (73-86%) in 2 h. No additional ligand or volatile solvent was required and the conversion was ecofriendly. Copyright