1374348-25-0

Basic information

• Product Name: 2-(phenylethynyl)-5-(pyridin-3-yl)-1,3,4-oxadiazole
• Synonyms: 2-(phenylethynyl)-5-(pyridin-3-yl)-1,3,4-oxadiazole
• CAS NO: 1374348-25-0
• Molecular Weight: 247.256
• Mol File: 1374348-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(phenylethynyl)-5-(pyridin-3-yl)-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylethynyl)-5-(pyridin-3-yl)-1,3,4-oxadiazole(1374348-25-0)
• EPA Substance Registry System: 2-(phenylethynyl)-5-(pyridin-3-yl)-1,3,4-oxadiazole(1374348-25-0)

Safety Data

• Hazardous Substances Data: 1374348-25-0(Hazardous Substances Data)

Upstream product

• 65943-95-5 2-(pyridin-3-yl)-1,3,4-oxadiazole 
• 637-44-5 phenylpropyolic acid 
• 100-52-7 benzaldehyde 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 553-53-7 Nicotinic acid hydrazide 

Relevant articles and documents

Palladium-Catalyzed Decarboxylative Cross-Coupling of 1,3,4-Oxa-diazoles with Alkynoic Acids: A Simple Route for the Preparation of 2-Alkynylated 1,3,4-Oxadiazoles

For the first time 2-alk-1-ynyl-5-(het)aryl-1,3,4-oxadiazole derivatives have been synthesized by the decarboxylative cross-coupling of alk-2-ynoic acids with 2-(het)aryl-1,3,4-oxadiazoles, employing palladium(II) chloride as the catalyst and silver(I) oxide as an oxidant with 1,3-bis(diphenylphosphanyl)propane as a ligand. Products were formed in high yields with no byproduct.