1374415-48-1

Basic information

• Product Name: C₂₆H₃₆N₂O₇
• Synonyms: C₂₆H₃₆N₂O₇
• CAS NO: 1374415-48-1
• Molecular Weight: 488.581
• Mol File: 1374415-48-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₆N₂O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₆N₂O₇(1374415-48-1)
• EPA Substance Registry System: C₂₆H₃₆N₂O₇(1374415-48-1)

Safety Data

• Hazardous Substances Data: 1374415-48-1(Hazardous Substances Data)

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 31954-27-5 N-(tert-butoxycarbonyl)glycine methyl ester 
• 194924-95-3 4-oxopyrrolidine-1,3-dicarboxylic acid 1-tert-butyl 3-methyl ester 
• 102124-10-7 tert-butyl 3-(benzylamino)propanoate 
• 1374415-40-3 1-tert-butyl 3-methyl 4-oxo-3-(2-oxo-2-phenylethyl)pyrrolidin-1,3-dicarboxylate 
• 15231-41-1 tert-butyl 3-aminopropanoate 

Relevant articles and documents

Preparation of new 1,4-diazocanes as scaffolds for combinatorial chemistry

Hexahydro-2-oxo-1,4-diazocin-6-carboxylic acid constitutes a conformationally rigid, crown-shaped scaffold. An orthogonally protected (Boc at N-4 and methyl ester at 6-CO2H) representative was prepared by ring expansion of a 3-pyrrolidone-derived 1,4-diketone with MeNH2. After deprotection, this building block was further diversified by reductive aminations and amidations and by sulfonamide and urea formation. Furthermore, the 6-CO2H function was transformed into a 6-NHCbz group in one step by carboxamide degradation in the presence of BnOH. An example of a cyclic tripeptoidic structure was synthesized by amidation with N-Boc-β-alanine and glycine methyl ester. Structural features of the eight-membered heterocycle were established by single-crystal X-ray structure analysis of a 4-bromoaniline derivative.