1374458-62-4

Upstream product

• 863324-53-2 (R)-1-(4-benzyl-2-thioxothiazolidin-3-yl)propan-1-one 
• 14371-10-9 (E)-3-phenylpropenal 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 1374458-68-0 tert-butyl{[(1R,2R,3R,4E)-1-{(1R)-2-[(tert-butyldiphenylsilyl)oxy]-1-methylethyl}-3-methoxy-2-methyl-5-phenyl-4-pentenyl]oxy}dimethylsilane 
• 1374458-67-9 (2R,3R,4S,5R,6E)-1-[(tert-butyldiphenylsilyl)oxy]-5-methoxy-2,4-dimethyl-7-phenyl-6-hepten-3-ol 
• 1374458-66-8 (2R,3R,4S,5R,6E)-5-methoxy-2,4-dimethyl-7-phenyl-6-heptene-1,3-diol 
• 1374458-61-3 {(2S,3S)-3-[(1R,2R,3E)-2-methoxy-1-methyl-4-phenyl-3-butenyl]-oxiran-2-yl}methanol 
• 1374458-65-7 {(2S,3S)-3-[(1R,2R,3E)-2-methoxy-1-methyl-4-phenyl-3-butenyl]-oxiran-2-yl}methanol 
• 1374458-64-6 ethyl (2E,4S,5R,6E)-5-methoxy-4-methyl-7-phenyl-2,6-heptadienoate 

Relevant academic research and scientific papers

Stereoselective synthesis of the C15-C30 subunit of dolabelides A-D

A highly stereoselective synthesis of the C15-C30 subunit of the cytotoxic macrolides dolabelides A-D has been accomplished by utilizing anti selective aldol reaction, Wittig olefination for the introduction of a trisubstituted (E)-double bond, selective hydroboration, Brown asymmetric allylation, Wilkinson hydrogenation and stereoselective keto reduction for the installation of C19 hydroxy group as key steps. The Royal Society of Chemistry 2013.

Towards the synthesis of (-)-callipeltoside A: Stereoselective synthesis of the C1-C14 macrolactone core

A highly stereoselective synthesis of the C1-C14 macrolactone core of the cytotoxic macrolide (-)-callipeltoside A has been achieved by utilizing an anti-selective aldol reaction and Wittig olefination to introduce an (E)-trisubstituted alkene, chemoselec