1374458-62-4

Basic information

• Product Name: (2R,3R,E)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-hydroxy-2-methyl-5-phenylpent-4-en-1-one
• Synonyms: (2R,3R,E)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-hydroxy-2-methyl-5-phenylpent-4-en-1-one
• CAS NO: 1374458-62-4
• Molecular Weight: 397.562
• Mol File: 1374458-62-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R,E)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-hydroxy-2-methyl-5-phenylpent-4-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,E)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-hydroxy-2-methyl-5-phenylpent-4-en-1-one(1374458-62-4)
• EPA Substance Registry System: (2R,3R,E)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-hydroxy-2-methyl-5-phenylpent-4-en-1-one(1374458-62-4)

Safety Data

• Hazardous Substances Data: 1374458-62-4(Hazardous Substances Data)

Upstream product

• 863324-53-2 (R)-1-(4-benzyl-2-thioxothiazolidin-3-yl)propan-1-one 
• 14371-10-9 (E)-3-phenylpropenal 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 1374458-63-5 ethyl (2E,4S,5R,6E)-5-hydroxy-4-methyl-7-phenyl-2,6-heptadienoate 
• 1374458-64-6 ethyl (2E,4S,5R,6E)-5-methoxy-4-methyl-7-phenyl-2,6-heptadienoate 
• 1374458-65-7 {(2S,3S)-3-[(1R,2R,3E)-2-methoxy-1-methyl-4-phenyl-3-butenyl]-oxiran-2-yl}methanol 
• 1374458-61-3 {(2S,3S)-3-[(1R,2R,3E)-2-methoxy-1-methyl-4-phenyl-3-butenyl]-oxiran-2-yl}methanol 
• 1374458-66-8 (2R,3R,4S,5R,6E)-5-methoxy-2,4-dimethyl-7-phenyl-6-heptene-1,3-diol 
• 1374458-67-9 (2R,3R,4S,5R,6E)-1-[(tert-butyldiphenylsilyl)oxy]-5-methoxy-2,4-dimethyl-7-phenyl-6-hepten-3-ol 
• 1374458-68-0 tert-butyl{[(1R,2R,3R,4E)-1-{(1R)-2-[(tert-butyldiphenylsilyl)oxy]-1-methylethyl}-3-methoxy-2-methyl-5-phenyl-4-pentenyl]oxy}dimethylsilane 

Relevant articles and documents

Stereoselective synthesis of the C15-C30 subunit of dolabelides A-D

A highly stereoselective synthesis of the C15-C30 subunit of the cytotoxic macrolides dolabelides A-D has been accomplished by utilizing anti selective aldol reaction, Wittig olefination for the introduction of a trisubstituted (E)-double bond, selective hydroboration, Brown asymmetric allylation, Wilkinson hydrogenation and stereoselective keto reduction for the installation of C19 hydroxy group as key steps. The Royal Society of Chemistry 2013.