137447-97-3Relevant academic research and scientific papers
New Chiral Solvating Agents: 1,5-Benzothiazepines
Giordano, Claudio,Restelli, Angelo
, p. 785 - 788 (1991)
For the first time it is reported that 1,5-benzothiazepines (1a-e) (Figure 1) behave as effective chiral solvating agents (CSA) for NMR enantiomeric excess (ee) determination of different classes of compounds such as α-arylalkanoic acids, α-hydroxy acids,
Metal- and additive-free oxygen-atom transfer reaction: an efficient and chemoselective oxidation of sulfides to sulfoxides with cyclic diacyl peroxides
Gan, Shaoyan,Yin, Junjie,Yao, Yuan,Liu, Yang,Chang, Denghu,Zhu, Dan,Shi, Lei
supporting information, p. 2647 - 2654 (2017/04/03)
Metal- and additive-free oxidation of a series of sulfides/thioketones has been achieved using cyclic diacyl peroxides as mild oxygen sources. This protocol features simple manipulation, high chemo- and diastereoselectivity, and a broad substrate scope (up to 42 examples), tolerates many common functional groups, and is scalable and applicable to the late-stage sulfoxidation strategy. A preliminary mechanistic study by quantum mechanical calculations suggests that a single two-electron transfer process is energetically more favorable, and indicates the reactivity of cyclic diacyl peroxides distinct from conventional acyclic acyl peroxides.
