New Chiral Solvating Agents: 1,5-Benzothiazepines

Article abstract of DOI:10.1016/S0957-4166(00)80460-7

For the first time it is reported that 1,5-benzothiazepines (1a-e) (Figure 1) behave as effective chiral solvating agents (CSA) for NMR enantiomeric excess (ee) determination of different classes of compounds such as α-arylalkanoic acids, α-hydroxy acids,