13745-42-1

Upstream product

• 51-17-2 benzoimidazole 
• 103-71-9 phenyl isocyanate 
• 98-95-3 nitrobenzene 
• 10147-70-3 2-chloro-N-(2-nitrophenyl)acetamide 
• 897583-89-0 N-(2-nitrophenyl)-2-phenylamino-2-thioxoacetamide 
• 88-74-4 2-nitro-aniline 
• 4857-04-9 2-chloromethyl-1H-benzimidazole 
• 62-53-3 aniline 
• 90430-71-0 N-phenyl-1H-benzo[d]imidazole-2-carbothioamide 
• 127427-45-6 2-bromo-2,2-difluoro-N-phenyl-acetamide 
• 95-54-5 1,2-diamino-benzene 
• 19213-18-4 1-pyrrolidin-1-ylmethyl-1H-benzoimidazole 
• 10543-64-3 phenyl-oxalamide 

Relevant academic research and scientific papers

Desulfurizing agent for thioamides

Thioamides treated with thionyl chloride in an ionic liquid were successfully converted into amides.

HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE

Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.

S8-Catalyzed triple cleavage of bromodifluoro compounds for the assembly of N-containing heterocycles

An unprecedented S8-catalyzed selective triple-cleavage of bromodifluoroacetamides is disclosed for the first time. Valuable 2-amido substituted benzimidazoles, benzoxazoles and benzothiazoles were obtained in good to excellent yields in a casc

Synthesis and reactivity of monothiooxamides of the aminonitroarene series

Monothiooxamides containing aminonitrobenzene and aminonitropyridine fragments have been synthesized. A possibility to synthesize thioesters and fused imidazole and diazepine derivatives on their basis has been demonstrated. ; 2009 Springer Science+Busine

Synthesis of 2-Substituted Imidazoles and Benzimidazoles and of 3-Substituted Pyrazoles by Lithiation of N-(Dialkylamino)methyl Heterocycles

The lithiation of N-(dialkylamino)methyl (aminal) derivatives of imidazole, benzimidazole, and pyrazole (themselves readily available from parent heterocycles, formaldehyde, and a secondary amine) occurs smoothly at 2-, 2-, and 5-positions, respectively, upon treatment with n-butyllithium in ether or tetrahydrofuran.Reaction with electrophiles, and subsequent facile acid-catalyzed hydrolysis of the protecting group, provides 2-substituted imidazoles, 2-substituted benzimidazoles, and 3(5)-substituted pyrazoles in good overall yields.

Synthesis of benzimidazole-2-carboxylic acid amides from o-phenylenediamine and oxamic acid esters

A method for the preparation of N-R amides of benzimidazole-2-carboxylic acid on the basis of the reaction between o-phenylenediamine and esters of N-R oxamic acids was developed.