1374550-85-2

Upstream product

• 247155-24-4 4-methyl-N-(4-(trimethylsilyl)but-3-yn-1-yl)benzenesulfonamide 
• 161040-05-7 N-(but-3-yn-1-yl)-4-methylbenzenesulfonamide 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 1374550-56-7 C₈H₁₃NO 
• 1374550-54-5 1-(4-hydroxybut-1-yn-1-yl)cyclobutan-1-ol 
• 1374550-49-8 N-(4-(1-hydroxycyclobutyl)but-3-yn-1-yl)-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Formal synthesis of (-)-cephalotaxine based on a tandem hydroamination/semipinacol rearrangement reaction

Catalytic asymmetric formal synthesis of (-)-cephalotaxine has been accomplished based on an efficient tandem intramolecular hydroamination/ asymmetric semipinacol rearrangement reaction catalyzed by chiral silver phosphate. During the course of the study it was observed that an advanced intermediate could be obtained in enantiopure form by enantiomer separation on silica gel.