161040-05-7

Basic information

• Product Name: Benzenesulfonamide, N-3-butynyl-4-methyl-
• CAS NO: 161040-05-7
• Molecular Formula: C11H13NO2S
• Molecular Weight: 223.296
• Mol File: 161040-05-7.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-3-butynyl-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-3-butynyl-4-methyl-(161040-05-7)
• EPA Substance Registry System: Benzenesulfonamide, N-3-butynyl-4-methyl-(161040-05-7)

Safety Data

• Hazardous Substances Data: 161040-05-7(Hazardous Substances Data)

Upstream product

• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 927-74-2 3-Butyn-1-ol 
• 14044-63-4 but-3-yn-1-amine 
• 98-59-9 p-toluenesulfonyl chloride 
• 338463-00-6 N-(tert-butoxycarbonyl)-N-but-3-ynyl-4-methylbenzenesulfonamide 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 718633-51-3 N-1-(3-oxopropyl)-4-methyl-1-benzenesulfonamide 
• 59724-53-7 (±)-N-(2-hydroxypropyl)-4-methylbenzenesulfonamide 
• 70-55-3 toluene-4-sulfonamide 
• 14437-03-7 methyl tosylcarbamate 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 1066-54-2 trimethylsilylacetylene 
• 247155-24-4 4-methyl-N-(4-(trimethylsilyl)but-3-yn-1-yl)benzenesulfonamide 
• 23418-85-1 3-butyn-1-yl p-toluenesulfonate 

Downstream Products

• 293313-46-9 N-(But-3-ynyl)-N-(4-methylpenta-2,3-dienyl)-4-methylbenzenesulfonamide 
• 873424-61-4 N-[2-(4,5-dimethylcyclohexa-1,4-dienyl)ethyl]-4-methylbenzenesulfonamide 
• 575501-45-0 4-chloro-1,2,5,6-tetrahydro-1-tosylpyridine 
• 819868-11-6 N-but-3-ynyl-N-(4-hydroxy-1-methyl-but-2-enyl)-4-methyl-benzenesulfonamide 
• 819868-12-7 1-[[(4R)-(E)-4-(tert-butyldimethylsilyloxy)-4-methylbut-2-enyl]-(4-methylbenzenesulfonyl)amino]but-3-yne 
• 819868-08-1 methyl 5-[[(E)-4-(tert-butyldimethylsilyloxy)but-2-enyl]-(4-methylbenzenesulfonyl)amino]pent-2-ynoate 
• 165903-17-3 4-methyl-N-(3-methylenepent-4-enyl)benzenesulfonamide 

Relevant articles and documents

Synthesis of Polyheterocyclic Tropones by [2 + 2 + 2 + 1] Carbonylative Cycloaddition of Triynes

A direct synthesis of tropones (2,4,6-cycloheptatrienes) from simple preorganized triynes has been elaborated. This simple rhodium-catalyzed domino strategy allows one-pot access to fully substituted tropones in a 6-6-7-5 tetracyclic core in average to hi

Synthesis of Polysubstituted Fused Pyrroles by Gold-Catalyzed Cycloisomerization/1,2-Sulfonyl Migration of Yndiamides

Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. Here we report a cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides to form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that are relevant to medicinal chemistry. This functional group tolerant transformation can be achieved using Au(I) catalysis that proceeds at ambient temperature, and a thermally promoted process. The utility of the products is demonstrated by a range of reactions to functionalize the fused pyrrole core.

Silver-Catalyzed Annulation of Arynes with Nitriles for Synthesis of Structurally Diverse Quinazolines

An efficient silver catalyzed annulation reaction of aryne with nitriles to generate quinazolines is described. Arynes generated from triynes or tetraynes through a hexadehydro Diels-Alder reaction readily participated in an [A + 2B] mode of annulation with nitriles in the presence of AgSbF6 catalyst. The mechanism was explored by DFT calculations, which supports the silver-catalyzed formation of nitrilium ion as a key intermediate. This annulation generates an array of polysubstituted novel quinazoline derivatives with excellent regioselectivity.