1374601-00-9Relevant academic research and scientific papers
New linearly and angularly fused quinazolinones: Synthesis through gold(I)-catalyzed cascade reactions and anticancer activities
Patil, Nitin T.,Lakshmi, Pediredla G.V.V.,Sridhar, Balasubramanian,Patra, Sujata,Pal Bhadra, Manika,Patra, Chitta Ranjan
experimental part, p. 1790 - 1799 (2012/05/04)
A robust library-based approach to new fused quinazolinones by the development of gold(I)-catalyzed cascade reactions between 2- aminobenzohydrazides and alkynoic acids is documented. Selected compounds were administered to lung (A549) and breast cancer cells (MDA-MB-231 and MCF-7) in vitro and it was found that some successfully inhibited cell proliferation.
