30086-49-8

Basic information

• Product Name: 2-Amino-N'-phenylbenzohydrazide
• Synonyms: 2-Amino-N'-phenylbenzohydrazide
• CAS NO: 30086-49-8
• Molecular Formula: C₁₃H₁₃N₃O
• Molecular Weight: 227
• Mol File: 30086-49-8.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-N'-phenylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-N'-phenylbenzohydrazide(30086-49-8)
• EPA Substance Registry System: 2-Amino-N'-phenylbenzohydrazide(30086-49-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 30086-49-8(Hazardous Substances Data)

Usage

Description

2-Amino-N'-phenylbenzohydrazide is a hydrazide derivative with the molecular formula C13H12N4O. It is a chemical compound that belongs to a class of organic compounds containing a functional group with the structure HN-NH-CO-R. 2-Amino-N'-phenylbenzohydrazide has shown promising biological activities and potential applications in various fields, including organic synthesis, pharmaceutical research, and the development of new drugs.

Uses

Used in Organic Synthesis:
2-Amino-N'-phenylbenzohydrazide is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the formation of new compounds and structures.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-Amino-N'-phenylbenzohydrazide is utilized as a starting material or intermediate in the development of new drugs, owing to its unique chemical properties and potential to interact with biological targets.
Used in Antitumor Applications:
2-Amino-N'-phenylbenzohydrazide has been studied for its potential antitumor properties, making it a candidate for the development of cancer therapeutics. Its ability to inhibit certain enzymes and affect cellular processes may contribute to its antitumor activity.
Used in Anti-inflammatory Applications:
2-Amino-N'-phenylbenzohydrazide has also been investigated for its potential anti-inflammatory properties, which could be beneficial in the treatment of various inflammatory conditions and diseases.
Used in Neurodegenerative Disease Treatment:
2-Amino-N'-phenylbenzohydrazide has been explored for its potential use in the treatment of neurodegenerative diseases, where its biological activities may help alleviate symptoms or slow disease progression.
Overall, 2-Amino-N'-phenylbenzohydrazide is a versatile chemical compound with a wide range of potential applications in the fields of organic synthesis, pharmaceutical research, and medicine, particularly in the development of new drugs and treatments for various diseases.

Upstream product

• 610-14-0 2-nitrobenzyl chloride 
• 100-63-0 phenylhydrazine 
• 118-92-3 anthranilic acid 
• 75681-27-5 N'-phenyl-2-nitrobenzoylhydrazine 
• 118-48-9 isatoic anhydride 
• 64-17-5 ethanol 

Downstream Products

• 5958-14-5 3-anilino-2-thiotetrahydroquinazole-4-one  
• 67571-01-1 4a-methyl-1-phenyl-3,4,4a,5-tetrahydro-pyridazino[3,2-b]quinazoline-2,10-dione 
• 1375103-52-8 2-(2-bromophenyl)-3-(phenylamino)-2,3-dihydroquinazol-in-4(H)-one 
• 102079-45-8 3-(phenylamino)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one 
• 1375103-51-7 2-(4-nitrophenyl)-3-(phenylamino)-2,3-dihydroquinazolin-4(1H)-one 
• 1375103-54-0 2-(2,6-dichlorophenyl)-3-(phenylamino)-2,3-dihydroquinazolin-4(1H)-one 
• 1375103-53-9 3-(phenylamino)-2-p-tolyl-2,3-dihydroquinazolin-4(1H)-one 
• 1370643-45-0 C₂₀H₁₆IN₃O 
• 1374601-00-9 6a-methyl-6-(phenylamino)-6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione 
• 1374601-08-7 3a-octyl-4-(phenylamino)-2,3,3a,4-tetrahydropyrrolo[1,2-a]quinazoline-1,5-dione 
• 1374601-09-8 3a-ethyl-4-(phenylamino)-2,3,3a,4-tetrahydropyrrolo[1,2-a]quinazoline-1,5-dione 
• 1374600-89-1 3a-methyl-4-(phenylamino)-2,3,3a,4-tetrahydropyrrolo[1,2-a]quinazoline-1,5-dione 
• 1374600-98-2 3a'-methyl-4'-(phenylamino)-3a',4'-dihydro-1'H-spiro[cyclopentane-1,2'-pyrrolo[1,2-a]quinazoline]-1',5'(3'H)-dione 
• 1374600-99-3 3a'-methyl-4'-(phenylamino)-3a',4'-dihydro-1'H-spiro[cyclohexane-1,2'-pyrrolo[1,2-a]quinazoline]-1',5'(3'H)-dione 

Relevant articles and documents

Synthesis of quaternary carbon-centered indolo[1,2-a]quinazolinones and indazolo[1,2-a]indazolonesviaC-H functionalization

An unprecedented Ru(ii)-catalyzed Csp2-H bond activation and annulation reaction of phenylindazolones with diaryl-substituted alkynes and dialkyl-substituted alkynes provided efficient routes for the construction of all-carbon quaternary-centered indolo[1,2-a]quinazolinones and quaternary carbon-centered indazolo[1,2-a]indazolones, respectively. The indolo[1,2-a]quinazolinones were fomedviaCsp2-H activation, alkyne insertion and a 1,2-phenyl shift. Indazolo[1,2-a]indazolones were formed through a cascade reactionviathe formation of exocyclic double bonds containing indolo[1,2-a]quinazolinones.

Synthesis and anti-microbial / anti-malarial activity of a new class of chromone-dihydroquinazolinone hybrid heterocycles

A new series of chromone-2,3-dihydroquinazolin-4-one hybrid heterocycles are synthesized from chromone-2-carbaldehydes by coupling with 2-Aminoarylamides and hydrazides without oxidizing agents. The newly synthesized products exhibited moderate to good antimicrobial activity.

Anti-tumor pyrimidine compounds and preparation method thereof

The invention belongs to the field of medicines and particularly relates to anti-tumor pyrimidine compounds and a preparation method thereof. The compounds belong to novel VEGFR (vascular endothelial growth factor receptor)-2 inhibitors and show good inhi