1374647-59-2

Basic information

• Product Name: methyl (2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine-2-carboxylate
• Synonyms: methyl (2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine-2-carboxylate
• CAS NO: 1374647-59-2
• Molecular Weight: 501.741
• Mol File: 1374647-59-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine-2-carboxylate(1374647-59-2)
• EPA Substance Registry System: methyl (2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine-2-carboxylate(1374647-59-2)

Safety Data

• Hazardous Substances Data: 1374647-59-2(Hazardous Substances Data)

Upstream product

• 129430-93-9 methyl (2S,4R)-4-hydroxy-1-tritylpyrrolidine-2-carboxylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1374647-37-6 [(2S,4R)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidin-2-yl]methanol 
• 1374647-55-8 (2S,4R)-2-(azidomethyl)-4-(tert-butyldimethylsilyloxy)-1-tritylpyrrolidine 
• 1374647-52-5 (3R,5R)-3-azido-5-(tert-butyldimethylsilyloxy)-1-tritylpiperidine 

Relevant articles and documents

Access to optically active 3-aminopiperidines by ring expansion of prolinols: Thermodynamic versus kinetic control

3-Aminopiperidines are of great interest because they can possess a wide range of biological activity depending on the nitrogen substituents. Different approaches their synthesis are presented and the most efficient is a ring expansion of prolinols induce