137474-32-9 Usage
Uses
Used in Organic Synthesis:
N,N-dimethyl-1-(trimethylsilyl)methanesulfonamide is used as a reagent in organic synthesis for its ability to protect amines during reactions, ensuring the selective formation of desired products without unwanted side reactions.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, N,N-dimethyl-1-(trimethylsilyl)methanesulfonamide is utilized as a key intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds with improved therapeutic properties.
Used in the Conversion of Alcohols to Silyl Ethers:
N,N-dimethyl-1-(trimethylsilyl)methanesulfonamide serves as a reagent for converting alcohols to silyl ethers, a transformation that is essential in the preparation of certain chemical intermediates and final products in organic chemistry.
Used in Fine Chemicals Production:
N,N-dimethyl-1-(trimethylsilyl)methanesulfonamide is also employed in the production of fine chemicals, where its unique properties allow for the creation of specialty chemicals used in various applications, including fragrances, dyes, and other high-value products.
Check Digit Verification of cas no
The CAS Registry Mumber 137474-32-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,4,7 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 137474-32:
(8*1)+(7*3)+(6*7)+(5*4)+(4*7)+(3*4)+(2*3)+(1*2)=139
139 % 10 = 9
So 137474-32-9 is a valid CAS Registry Number.
137474-32-9Relevant academic research and scientific papers
A PETERSON OLEFINATION REACTION USING SILYL-SUBSTITUTED SULFONAMIDE CARBANIONS. SYNTHESIS OF VINYLIC SULFONAMIDES
Mladenova, Margarita,Gaudemar-Bardone, Francoise
, p. 257 - 268 (2007/10/02)
α-Trimethylsilyl-substituted sulfonamides RCH(SiMe3)SO2N(CH3)2 (3), (R=H, CH3 and C6H5) are synthesized in almost quantitative yields.Their lithium derivatives 4 undergo a smooth Peterson olefination reaction with nonenolisable carbonyl compounds to give good to excellent yields of vinylsulfonamides 6.With R=H, the reaction is highly E-stereoselective.Moderate stereoselectivity is obtained in the cases of R=CH3, and R=C6H5.Key words: Peterson olefination reaction; N,N-dimethyl α-trimethylsilylsulfonamides; α-trimethylsilyl-substituted sulfonamide carbanions; vinylic sulfonamides; stereochemistry.
