1374852-07-9Relevant academic research and scientific papers
Photoremovable chiral auxiliary
Kammath, Viju Balachandran,Sebej, Peter,Slanina, Tomas,Ki, Zdenek,Klan, Petr
, p. 500 - 507 (2012/06/30)
A new concept of a photoremovable chiral auxiliary (PCA), based on the chiral benzoin chromophore, is introduced. This moiety can control the asymmetric formation of a Diels-Alder adduct, and then be removed in a subsequent photochemical step in high chemical and quantum yields. Selective formation of the products at up to 96% ee was observed in the presence of a Lewis acid catalyst in the case of a 2-methoxybenzoinyl chiral auxiliary.
