1374882-99-1Relevant academic research and scientific papers
An alkyne hydroacylation route to highly substituted furans
Lenden, Philip,Entwistle, David A.,Willis, Michael C.
, p. 10657 - 10660 (2012/01/04)
More rings for your rhodium: Rhodium-catalyzed intermolecular alkyne hydroacylations deliver γ-hydroxy-α,β-enones, which can be cyclized in situ to deliver di-and trisubstituted furans. Functionalization of the intermediates using Heck chemistry allows the formation of regioisomeric furans. The use of an alternative RhI catalyst delivers 1,4-dicarbonyl compounds and hence pyrroles, thiophenes, and pyridazines, all from the same two starting materials. Copyright
