137496-86-7Relevant academic research and scientific papers
SYNTHESIS OF (+/-)-SENOXEPIN - THE FIRST NATURALLY OCCURING ANTI-HUECKEL OXEPIN DERIVATIVE
Cleve, A.,Bohlmann, F.
, p. 1241 - 1244 (1989)
The first total synthesis of (+/-)-senoxepin 3 is described. 3 is prepared via an intramolecular cycloaddition from a substituted decadienyne 7.The resulting hexalin 8 was converted to a lactone, which on epoxidation, NBS bromination and elimination with NaI afforded senoxepin.
